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Pregnancy Among HIV-Serodiscordant Couples: Case Report of Vertical Transmission and Retrospective Case Series.
CONCLUSION: Despite concerted attempts to minimize HIV transmission during pregnancy and breastfeeding in our wellresourced setting, residual transmission risk remains due to non-suppressed viral load within many HIV-serodiscordant pregnant couples.
PMID: 33390144 [PubMed - as supplied by publisher]
Source: Current HIV Research - December 31, 2020 Category: Infectious Diseases Authors: Choudhury B, Stadnyk M, Jijon DF, McLaughlin L, Kanji JN, Charlton C, Smyczek P, Vaudry W, Houston S, Tse-Chang A, Hawkes MT Tags: Curr HIV Res Source Type: research
Late diagnosis, delayed presentation and late presentation among persons enrolled in a clinical HIV cohort in Ontario, Canada (1999 –2013)
ConclusionsLate presentation is common in Ontario, as it is in other high ‐income countries. Our findings suggest that efforts to reduce late presentation should focus on facilitating earlier diagnosis for the populations identified in this analysis.
Source: HIV Medicine - November 14, 2018 Category: Infectious Diseases Authors: J Wilton,
L Light,
S Gardner,
B Rachlis,
T Conway,
C Cooper,
P Cupido,
CE Kendall,
M Loutfy,
F McGee,
J Murray,
J Lush,
A Rachlis,
W Wobeser,
J Bacon,
AE Kroch,
M Gilbert,
SB Rourke,
AN Burchell, on behalf of
Ontario HIV Treatment Netwo Tags: Original Research Source Type: research
Lost but not forgotten: A population ‐based study of mortality and care trajectories among people living with HIV who are lost to follow‐up in Ontario, Canada
ConclusionsMortality risk and use of health care resources were lower among active cohort participants. Our findings may inform health outcome estimates based on volunteer cohorts, as well as quantitative bias adjustment to correct for such biases.
Source: HIV Medicine - November 26, 2018 Category: Infectious Diseases Authors: CE Kendall,
J Raboud,
J Donelle,
M Loutfy,
SB Rourke,
A Kroch,
C Liddy,
R Rosenes,
Ontario HIV Treatment Network (OHTN) Cohort Study Team,
AN Burchell,
Jeffrey Cohen,
Don Kilby,
Fred Crouzat,
Nisha Andany,
Nicole Mittmann,
Irving Salit,
Mi Tags: Original Research Source Type: research
People Living With HIV Have Slightly Higher Incidence of COPD, Study Confirms People Living With HIV Have Slightly Higher Incidence of COPD, Study Confirms
The incidence of chronic obstructive pulmonary disease (COPD) is slightly but significantly higher among people living with HIV than among HIV-negative people, and it may have to do with smoking, according to a retrospective study from Canada.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - February 21, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news
Recent advances in HIV-associated chronic lung disease clinical research
Purpose of review
To highlight recently published, clinically focused research on chronic lung disease in adult persons with human immunodeficiency virus-1 (HIV) (PWH).
Recent findings
Chronic lung disease was the most common comorbidity in hospitalized PWH in New York and second-most common condition in ambulatory PWH in Canada. The elevated risk of chronic obstructive pulmonary disease in PWH has been widely recognized, but PWH are also at higher risk for asthma and worse asthma outcomes. Expanded assessments of lung structure and function, such as single-breath diffusing capacity of carbon monoxide (DLCO), ex...
Source: Current Opinion in HIV and AIDS - May 1, 2021 Category: Infectious Diseases Tags: HIV-ASSOCIATED CO-MORBIDITIES: Edited by Morris Schambelan and Todd T. Brown Source Type: research
HPV Infection in Pregnancy Higher Among Women Living With HIV HPV Infection in Pregnancy Higher Among Women Living With HIV
Pregnant women living with HIV have a higher prevalence of HPV infection than do pregnant women without HIV, researchers in Canada and Denmark report in an analysis with public health implications.Medscape Medical News
Source: Medscape Hiv-Aids Headlines - October 6, 2022 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news
Kenya: Kenya May Lose HIV/Aids Funding if U.S. Makes no Resolution on Kenyan MPs' Request
[allAfrica] Harare -- Kenya might stop receiving funds for HIV if a decision in the U.S. Congress is not made by the end of the month, according to Business Insider Africa.
Source: AllAfrica News: HIV-Aids and STDs - September 1, 2023 Category: Infectious Diseases Tags: Aid and Assistance HIV-Aids and STDs East Africa External Relations Governance Health and Medicine Kenya Sustainable Development United States, Canada and Africa Source Type: news
Donating One's Body to HIV Cure Research Through Canadian Medical Assistance in Dying: A Case Study
CONCLUSION: Several circumstances facilitated the patient's participation: being a single man, having time to participate, having no strong religious belief, and valuing clear, direct communication. His motivations to participate in HIV cure research were altruistic, and also an experience of working with clinical and research teams. Finally, this perspective highlights HIV cure research participant candidates' need for education about research procedures.PMID:37670698 | DOI:10.2174/1570162X21666230904150923
Source: Current HIV Research - September 6, 2023 Category: Infectious Diseases Authors: David Lessard Bertrand Lebouch é Andr é Morneau Martin Bilodeau Ron Rosenes Justin Sanders Nicolas Chomont Patrick Keeler Karine Dub é Shari Margolese Mohammad-Ali Jenabian Christopher Power Jean-Pierre Routy Jonathan B Angel Eric A Cohen Cecilia T Cos Source Type: research
Subclinical Atherosclerosis Is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in Long-Term HIV Treated Individuals
We report that blood levels of BAFF are elevated and correlate positively with CVD and its risk factors in PLHIV from the CHACS, in contrast to APRIL levels, which correlate negatively with these factors. The expression levels of Breg markers such as NR4A3, CD39, CD73 and CD83 are significantly lower in PLHIV when compared to those of HIV-uninfected controls. In vitro experiments show that APRIL upregulates the expression of Breg markers by blood MZp from HIV-uninfected individuals, while this modulation is dampened by the addition of recombinant BAFF. Altogether, our observations suggest that strategies viewed to modulate...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Matheus Aranguren Kim Doyon-Lalibert é Mohamed El-Far Carl Chartrand-Lefebvre Jean-Pierre Routy Jean-Guy Barril Beno ît Trottier C écile Tremblay Madeleine Durand Johanne Poudrier Michel Roger Canadian HIV and Aging Cohort Study Source Type: research
Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study
Publication date: Available online 23 July 2017 Source:The Lancet HIV Author(s): Jean-Michel Molina, Isabelle Charreau, Bruno Spire, Laurent Cotte, Julie Chas, Catherine Capitant, Cecile Tremblay, Daniela Rojas-Castro, Eric Cua, Armelle Pasquet, Camille Bernaud, Claire Pintado, Constance Delaugerre, Luis Sagaon-Teyssier, Soizic Le Mestre, Christian Chidiac, Gilles Pialoux, Diane Ponscarme, Julien Fonsart, David Thompson, Mark A Wainberg, Veronique Doré, Laurence Meyer Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We implemented a cohort study to assess its efficacy, safety, and effect on sexua...
Source: The Lancet HIV - July 24, 2017 Category: Infectious Diseases Source Type: research
